|
|
Opinion Polls & Market Research
Which Cartridge Design is Best for Your Application
The Anatomy of Sep-Pak Plus and Classic Cartridge Designs
1 Female Luer inlet accepts male Luer tip. Plus cartridge design
can be stacked.
2 Highest quality sorbents designed and made specially for
sample
preparation;
clean, dry, reproducible in activity and capacity, with optimal surface
area pore and particle size distributions.
3 Broad range of sorbent surface activities available; each
lot is
tested
under rigid specifications for chromatographic activity, retention and
selectivity.
4 Sorbent type and bed dimensions equal to corresponding
Sep-Pak
Classic
cartridges enable direct transfer of previously developed and published
methods to new Plus design.
5 Weight of sorbent in each cartridge is controlled within +/-
5% of
specification to assure reproducible performance.
6 Advanced bed formation technology to minimize voids and
channels.
6* Patented Radial Compression Technology used to form
homogeneous
packed
bed free of voids and channels.
7 Special blend of HD and UHMW polyethylenes used for 20
micron
frits
imparts excellent solvent resistance, extremely low extractables level,
and good flow properties. Frit also acts as depth filter for small
amounts
of sample debris.
8 Polyethylene body has excellent solvent resistance. All body
parts
are quality tested to verify extremely low level of UV-absorbing
extractables.
Plus design is molded for precise dimensions making it suitable for
automated
equipment.
9 Cartridges are sealed in a special polyfoil pouch to protect
product
integrity, sorbent activity and purity.
10 Male Luer outlet has reduced internal volume for minimal
sample
hold-up.
11 Color-coded ring compresses and seals the cartridge and
identifies
sorbent.
*P.D. McDonald, C.W. Rausch, Radial Compression of Packed
Beds, U.S.
Patent #4,250,035 (1981); Great Britain #1,569,700 (1976); Canada
#1,101,785
(1981); Japan #1,400,983 (1987); Sweden #450,750 & #453,437 (1987);
Germany #2,655,650 (1988); other patents pending.
The Anatomy of Sep-Pak Vac and Vac RC Cartridge Designs
1 Highest quality sorbents designed and made specially for sample
preparation; clean, dry, reproducible in activity and capacity, with
optimal
surface area pore and particle size distributions.
2 Broad range of sorbent surface activities available; each
lot is
tested
under rigid specifications for chromatographic activity, retention and
selectivity.
3 Weight of sorbent in each cartridge is controlled within +/-
5% of
specification to assure reproducible performance.
4 Special blend of HD and UHMW polyethylenes used for 20
micron
frits.
5 Molded, medical grade polypropylene body.
6 Cartridges are sealed in a special polyfoil pouch to protect
product
integrity, sorbent activity and purity.
7 Integral reservoir approximately 20 mL, robotic compatible.
8 Outlet male Luer tip.
9 Color-coded labeling on the cartridge to identify the
sorbent.
Sep-Pak cartridges are available in a variety of designs; each
offers
specific functional benefits but all contain the same high-quality
packing
sorbents. This makes transfer of methods from one design to another
straightforward
and predictable. Refer to diagrams of the various cartridges designs,
and
Table 5 for sorbent weights.
Sep-Pak Plus Cartridges for Maximum Versatility
Sep-Pak Plus cartridges are designed for both convenient manual use and compatibility with automated instruments. They come in short body and long body configurations and are constructed from high purity polyethylene with female Luer inlets and male Luer outlets. They can be connected to many different types of devices such as positive flow pumps and syringes, vacuum manifolds, and automated sample processors.In many applications, the use of positive flow (pumps)
provides for
increased reproducibility in your results. Variations in recovery data,
due to flow rate variability and the potential for air drying out a
cartridge
when using vacuum devices, can be eliminated.
The male outlet tips feature reduced hold-up volume for
precise
fraction
collection. The fittings also allow cartridges to be easily stacked for
increased capacity or for the use of more than one sorbent type for
cleanup
of complex sample mixtures.
Sep-Pak Plus cartridges can be used with liquid or gas samples
and
have
the unique capability for reverse flow direction, a useful feature for
trace enrichment applications. The packing process and compression seal
provide a uniform bed structure to minimize band spreading for the best
possible separation efficiency.
Interstitial volumes and weights of sorbent in the short and
long
body
cartridges equal those of the corresponding Classic cartridges.
All Sep-Pak Plus cartridges have color-coded compression rings
for
general
sorbent identification.
Sep-Pak Classic Cartridges
Sep-Pak Classic cartridges were the original SPE cartridges introduced over 15 years ago. Our Sep-Pak Classic cartridges contain the same amount of sorbent as the Sep-Pak Plus cartridge. This means that you can convert existing methods easily to the more convenient Plus configuration.Both the Sep-Pak Plus and Classic designs have two different
sizes
(short
body and long body) depending on the type of sorbent.
Short Body Long Body
Sep-Pak Plus C18, tC18, C8, tC2 Silica, Florisil,
Accell Plus QMA Alumina A, B, N
and CM, NH2, CN, Environmental C18
Diol and tC18
Sep-Pak Classic C18, Accell Plus QMA Silica, Florisil,
and CM, NH2, CN, Alumina A, B, N
Diol
Sep-Pak Environmental Cartridges
This is a special "long body" Plus cartridge design containing approximately 1 gram of the monofunctional C18 or the trifunctional C18 sorbent. These cartridges are especially useful in trace enrichment applications.Sep-Pak Light Cartridges for Limited Sample Volumes/Lower Solvent
Sep-Pak Light cartridges look similar to the short-body Sep-Pak Plus cartridges, except for the distinctive "finned" outer body. The functional difference is the reduced internal diameter which results in an interstitial volume about one-third that of the corresponding Plus cartridge. This design allows you to elute fractions in a minimal volume to improve recoveries and reduce solvent consumption, a benefit especially for "sample-limited" applications or where excessive dilution is a concern.In addition, the Sep-Pak Light cartridges are especially
designed to
provide efficient packed sorbent beds for use in downsizing current
applications
to reduce solvent consumption.
All Sep-Pak Light cartridges have color-coded compression
rings for
general sorbent identification.
Economical Sep-Pak Vac Cartridges
Sep-Pak Vac cartridges provide you with the option of even lower cost sample preparation. The cartridges use molded polypropylene "syringe barrel" bodies and two polyethylene filters to contain the packing material. A standard male Luer outlet tip permits use with most multi-position vacuum manifolds. Cartridge sizes range from 1 cc to 35 cc and sorbent weights range from 50 mg up to 10 grams.Sizes up to 6 cc can be used on many automated sample
preparation
systems
designed to use "syringe barrel" style cartridges. Sep-Pak Vac
cartridges
offer the highest quality at low cost with a complete range of
capacities
for use in optimizing your methods.
Color-coded printing on the syringe barrels makes sorbent
identification
easy.
Sep-Pak Vac RC Cartridges for Manual or Robotic Sample Preparation
These cartridges feature a 20 cc "funnel" shape design containing 100 or 500 mg of sorbent. They can be used with robotic sample preparation equipment or with vacuum manifolds. The integral reservoir design allows for the convenient processing of larger amounts of sample or solvents. This reduces set-up time and costs associated with the use of separate reservoirs.Color-coded printing on the cartridges makes sorbent
identification
easy.
Sep-Pak Vacuum Manifolds
The 16 position cartridge unit is especially suited for our new robotic compatible cartridges.
These new manifolds offer you an economical way to "batch" process many samples at one time. The glass vacuum vessel allows you to see the progress of your sample processing. These manifolds are available in three capacities- 12 position
- 16 position (ideal for Sep-Pak Vac RC cartridges)
- 24 position
Adjustable racks inside the glass walled vacuum chamber accommodate a variety of collection vessels including autosampler vials, test tubes, scintillation vials and volumetric flasks. Eluents are deposited directly into the collection vessel via polypropylene or optional stainless steel delivery needles. A vacuum bleed valve and vacuum gauge attached to the chamber allows the amount of vacuum employed to be controlled by the analyst. The vacuum manifold is easily cleaned and is made from chemically inert materials.
|
|
Medtechnica-analytical department
Who else has been visiting this website? רוצים לראות מי עוד מבקר באתר